What is Melatonin?
Melatonin (/ˌ mɛ lə toʊ nɪn/), also known as the chemical N-acetyl-5-methoxytryptamine, is a hormone that exists naturally in most animals, including humans, and some living organisms. other living organisms, including algae. Circulation levels depend on daily life cycles, and melatonin plays an important role in maintaining the normal rhythm of a number of physiological functions. Many of the biological effects of melatonin are produced by the action of melatonin inducers, while others have a role in controlling and potent antioxidants with the specific function of protecting nuclear and mitochondrial DNA.
Melatonin is a hormone naturally produced in the body by the pineal gland of the brain. This hormone helps regulate circadian rhythm, also known as the body’s natural biological clock.

Melatonin concentration changes depending on light:
At night: melatonin levels start to increase about 2 hours before bed, promoting us to become sleepy.
In the morning: when light hits the eyes, it signals the brain to stop producing melatonin and we become more alert.
In the human body, this melatonin hormone gradually decreases with age. As you get older, this hormone will secrete less and less, causing older people to sleep less and have more difficulty sleeping than young people. Melatonin is a hormone that plays a role in regulating sleep.

The functions of Melatonin

1. Supports treatment of jet lag
   Jet lag is a condition of insomnia caused by jet lag after traveling to a distant land by plane. Using melatonin can help regulate the normal circadian rhythm of the day-night cycle to help you sleep better.
2. Supports delayed sleep phase disorder (DSWPD)
   You often have difficulty falling asleep or sleeping very intermittently when you have late sleep-wake phase disorder. This often happens when bedtime is more than 2 hours later than usual or when working shifts and needing to sleep in the morning. Studies have shown that melatonin is effective in reducing the time it takes to fall asleep to help increase the amount of sleep time and improve sleep quality. Thanks to that, you can ensure sleep quality even if your schedule changes a bit. Melatonin helps people fall asleep faster in people with late sleep-wake phase disorder. Supports the treatment of sleep disorders in children. Melatonin also helps regulate sleep schedules and timing in children with short-term or temporary sleep disorders. However, melatonin is a hormone in nature, so when used for a long time, it can affect pubertal development and children’s growth activities. Therefore, parents should not arbitrarily let children use melatonin. If there is a need to use medication, parents need to take their baby to see a doctor for examination and the most appropriate prescription for melatonin.
3. Improve anxiety before and after surgery
   Anxiety before and after surgery is a condition that can occur in 80% of patients. This makes it difficult for patients to sleep and insomnia affects the treatment results. Some studies on 774 people have also shown that melatonin has a sedative role, reducing anxiety disorders similar to the drug midazolam for patients.
4. Helps treat insomnia
   Melatonin is often referred to as the sleep hormone, and is one of the most popular sleep aids with the following effects:
   – Improve sleep time. Extend sleep time and quality.
   – People should take melatonin two hours before going to bed to help people fall asleep faster and improve sleep quality.
5. Helps reduce symptoms of seasonal depression
   Seasonal affective disorder (SAD), also known as seasonal depression, is a common condition. The disease, which often appears in late fall to early winter, is often related to changes in your circadian rhythm due to seasonal changes in light. Melatonin plays a role in regulating the body’s circadian rhythm. Therefore, low doses of melatonin may be used to assist in relieving symptoms of seasonal depression.
6. Improve eyesight
   Melatonin contains many antioxidants, which can help reduce cell damage, prevent macular degeneration and keep eyes healthy. According to NCBI research, melatonin may be beneficial in the treatment of glaucoma and age-related macular degeneration (AMD).
7. Helps reduce symptoms of gastroesophageal reflux (GERD)
   Gastroesophageal reflux (GERD) is a condition in which digestive fluids from the stomach move back up into the esophagus, causing damage to the mucosa. This causes the patient to feel burning, belch and have difficulty swallowing. Melatonin has been shown to block the secretion of gastric acid in the stomach, reducing the production of nitric oxide (NO), a compound that relaxes the lower esophageal sphincter. This can reduce the symptoms of gastroesophageal reflux disease. Although there have been many studies showing effectiveness, melatonin has not yet been approved for use in GERD. Therefore, patients need to consult a doctor or pharmacist if they want to use melatonin to treat the disease.
8. Stimulates growth hormone
   Human growth hormone (GH) is a hormone important for cell growth and regeneration, which is associated with increased strength and muscle mass. Some studies show that using melatonin can be effective in improving growth hormone in men.
9. Supports against neurodegeneration
   A decrease in melatonin levels in the body can be the cause of neurodegenerative diseases such as Parkinson’s or Alzheimer’s. Therefore, supplementing melatonin from outside can help slow down the progression of the disease.
10. Support anti-aging
    Reduced melatonin production by the pineal gland is one of the main causes of premature aging. Therefore, to improve this condition, in addition to maintaining a healthy lifestyle, you can supplement melatonin and antioxidants daily.

Nano Melatonin is produced using modern Nano technology

Nano technology has overcome the weakness of Melatonin’s poor absorption by reducing Melatonin to a microscopic form with a size of 20-30nm without completely changing the original chemical structure and biological nature. , providing products with high safety, outstanding efficiency and speed. This ultra-small size and new generation targeted packaging will help Nano Melatonin be completely soluble in water, increasing bioavailability hundreds of times compared to normal molecular size.

The process of formulating the Nano Melatonin microemulsion system by OIC NEW

The process of formulating the Nano Melatonin microemulsion by OIC NEW has been granted Utility Solution Patent No. 2491 by the Intellectual Property Office.

Nano Melatonin liquid material is superior thanks to:

• Melatonin ingredients from high purity beef glands and auxiliary ingredients imported from the US and EU meet international pharmacopoeia standards.
• The size of medicinal medicinal particles is extremely small, below 30 nm.
• Melatonin Nanoparticles are spherical, stable, and not destroyed by gastric acid.
• Microemulsion form completely dissolves in water, absorbing 99.9% into blood and cells.
• Exclusive PEG and PLA encapsulating membranes target the exact location of the injury.
• Nano Melatonin is hundreds of times more effective than regular Melatonin.

Packaging specifications and packaging materials

Packaging: 0.5 liters, 1 liter, 2 liters, 3 liters, 4 liters, 5 liters, 10 liters, 15 liters, 20 liters.
Close the glass jar or plastic container. Packaging meets quality standards used in food according to regulations of the Ministry of Health.
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For detailed information about ordering nano materials, please contact:
Nhat Hai New Technology Joint Stock Company – OIC NEW
No. 42, BT2, Linh Dam Peninsula, Hoang Liet Ward, Hoang Mai District, Hanoi.
Hotline: 1900 63 69 13