EFFECTS OF CURCUMIN IN SUPPORTING THE TREATMENT OF ALZHEIMER
Alzheimer’s is an irreversible degenerative brain disease with severe cognitive, behavioral and physical impairments that affect patients’ daily lives and require caregivers.
Alzheimer’s is an irreversible degenerative brain disease with severe cognitive, behavioral and physical impairments that affect patients’ daily lives and require caregivers.
Alzheimer’s is more common in older people and can be caused by environmental, genetic, or lifestyle factors.
Currently, there is no cure for Alzheimer’s disease, instead there are therapies and drugs to improve symptoms in the short term, allowing Alzheimer’s patients to maintain social control for a long time. longer time.
In recent studies, scientists have confirmed the use of Curcumin for the prevention and treatment of Alzheimer’s disease.
Curcumin may improve Alzheimer’s status through:
- Prevents beta amyloid plaque accumulation.
Breaks up the accumulation of beta amyloid plaques. Like many polyphenols, Curcumin acts on inflammatory factors, growth factors, cytokines and enzymes. A study published in the “Journal of Alzheimer’s disease” in 2011 demonstrated:
Curcumin has the ability to directly bind and prevent the formation of beta amyloid plaques.
Thus, slowing down the degradation of neurons and synapses (neurotransmitters) helps to improve the memory of Alzheimer’s patients.
Helps reduce cholesterol in the brain (high cholesterol levels are linked to dementia risk in Alzheimer’s patients).
- Natural anti-inflammatory
When studying Alzheimer’s disease, experts have observed neuroinflammation or inflammation of the brain, which is caused by trauma, exposure to oxidizing agents, infection, and the formation of beta amyloid plaques.
Curcumin may be a natural alternative to anti-inflammatory drugs and may help reduce the risk of neuroinflammation.
A study published in the International Neurochemical Research Institute in 2016 identified that curcumin is one of the agents that reduce brain inflammation in Alzheimer’s disease.
- Antioxidant support
Heavy metal exposure increases the risk of heavy metal accumulation in the brain causing inflammation and the accumulation of beta-amyloid plaques in the brain.
Curcumin derivative was found to inhibit the accumulation of heavy metals in Alzheimer’s disease.
A study published in Food Chemistry in 2016 analyzed the role of different dietary antioxidants in the treatment of Alzheimer’s disease. They act as metal chelators, forming reactive oxygen species that block and inhibit the formation of beta-amyloid plaques.
Among the antioxidants studied, curcumin has been identified as providing many benefits for the treatment and prevention of Alzheimer’s disease including modification or removal of heavy metals.
Research has demonstrated that Curcumin reduces oxidative stress clearly in animal studies with Alzheimer’s disease and thereby reduces brain cell degeneration.
Curcumin’s antioxidant capacity offers significant contributions to the prevention of Alzheimer’s disease and neuroprotection.
- Protects memory and cognition.
Curcumin has the ability to enhance memory for people with Alzheimer’s disease.
Curcumin protects nerve cells and improves learning and memory in people with Alzheimer’s disease. A study published in the journal Plos One 2015 showed that curcumin improves cognitive function in Alzheimer’s disease by raising levels of BDNF, a protein that supports nerve growth. Thanks to its antioxidant properties, curcumin can prevent the sudden onset of Alzheimer’s disease.
- Curcumin inhibits the development of Alzheimer’s disease.
An article published in the British Journal of Nutrition in 2016 suggests that curcumin may prevent Alzheimer’s disease by blocking the deposition of beta-amyloid plaques, affecting its metabolism and preventing cognitive dysfunction.
The expression of certain genes inevitably leads to the development of Alzheimer’s disease. Dietary curcumin and polyphenol compounds may prevent genomic instability.
Histone deacetylase is an enzyme that regulates DNA formation and gene expression. Curcumin inhibits this enzyme and prevents the development of Alzheimer’s disease. Curcumin has been found to have a better preventive effect than a cure for Alzheimer’s disease.
The blood-brain barrier is a special physiological barrier of humans, they help prevent unwanted agents from entering the bloodstream from freely entering the brain. With drugs that act on the central nervous system, this blood-brain barrier becomes a major barrier to limiting or even making the drug ineffective.
According to a study published in “The Journal of Biological Chemistry” in December 2004. Nano-sized curcumin particles can cross the blood-brain barrier.
Dr. Luu Hai Minh and the authors of Nhat Hai New Technology Joint Stock Company invented the product Liquid Nano Curcumin OIC, which was granted an exclusive patent number: 16095/QĐ-SHTT.
By applying Nano technology to reduce the particle size of Curcumin to Nano size (<39nm) completely soluble in water, absorption up to 98%.
Thanks to the Nano size <39nm, the sphere and the inert membrane will help absorb into the blood and regenerate in the circulatory system in the shortest time.
Liquid Nano Curcumin OIC will be a good choice for people with Alzheimer’s disease to support treatment.
The product is not a medicine, it is not a substitute for medicine!
The article is based on available research papers.
Source: The Journal of Biological Chemistry” December 2004, Journal of Alhzeimer’s disease” 2011, Nutrition Magazine (British magazine) 2010
